pentobarbital will minimize the extent or effect of fentanyl intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Closely. Coadministration of fentanyl with CYP3A4 inducers could lead into a minimize in fentanyl plasma concentrations, lack of efficacy or, maybe, advancement of a withdrawal syndrome inside of a… Read More